Exome sequencing is a strategy of genome sequencing whereby individual exons are coded rather than the entire genome. Due to its lower cost, exome sequencing is used by scientists to looking for genetic elements of disease.

Exome sequencing determines every exon in the genome. It is beneficial in searching for underlying causes of rare disorders since individual, rare mutations could be uncovered.

Exons are the parts of DNA that control coding and are expressed as proteins.