Calcium and vitamin D improve bone density in patients taking antiepileptic drugs

Many patients with epilepsy are required to take chronically an AED such as phenytoin, phenobarbital, carbamazepine, primidone, and valproate alone or in combination to control seizures. There is much medical evidence reporting that these AEDs may accelerate bone loss, increasing the risk of osteoporotic fractures.

Neurotechnology: BRAIN storm

Obama's vague announcement on 2 April had left out key details, such as what the initiative's specific goals would be and how it would be implemented. So at their first opportunity — a workshop convened on 6 May by the National Science Foundation (NSF) and the Kavli Foundation of Oxnard, California — researchers from across the neuroscience spectrum swarmed to fill in the blanks and advocate for their favourite causes.

Researchers discover how brain circuits can become miswired during development

The researchers describe, for the first time, that faulty wiring occurs when RNA molecules embedded in a growing axon are not degraded after they give instructions that help steer the nerve cell. So, for example, the signal that tells the axon to turn -- which should disappear after the turn is made -- remains active, interfering with new signals meant to guide the axon in other directions.

Gene found to foster synapse formation in the brain

Researchers at Johns Hopkins say they have found that a gene already implicated in human speech disorders and epilepsy is also needed for vocalizations and synapse formation in mice. The finding, they say, adds to scientific understanding of how language develops, as well as the way synapses — the connections among brain cells that enable us to think — are formed.

Study points to possible treatment for brain disorders

To better understand the process of neurogenesis, the researchers used a genetic approach known as neonatal electroporation to deliver pieces of DNA into neural stem cells in young mice, which allowed them to express and control specific components of the mTOR pathway.

The pig, the fish, and the jellyfish: Tracing nervous disorders in humans

The pig, the jellyfish and the zebrafish are being used by scientists at Aarhus University to, among other things, gain a greater understanding of hereditary forms of diseases affecting the nervous system. This can be disorders like Parkinson’s disease, Alzheimer’s disease, autism, epilepsy and the motor neurone disease ALS.

Researchers ferret out function of autism gene

Scientists say mutations in one such autism-linked gene, dubbed NHE9, which is involved in transporting substances in and out of structures within the cell, causes communication problems among brain cells that likely contribute to autism.

New Guidelines Released for Diagnosis, Surveillance and Management of Rare Genetic Disease Called Tuberous Sclerosis Complex

TSC is a genetic disease affecting approximately 50,000 in the United States and up to 1 million worldwide. It causes tumors to form in vital organs, primarily the brain, heart, kidneys, skin, eyes, liver and lungs. TSC is also the leading genetic cause of both epilepsy and autism. Currently, there is no cure.