{"id":452,"date":"2023-08-10T15:21:44","date_gmt":"2023-08-10T15:21:44","guid":{"rendered":"https:\/\/pediatricbrainfoundation.org\/archive\/mediator-med-complex\/"},"modified":"2023-08-10T15:21:44","modified_gmt":"2023-08-10T15:21:44","slug":"mediator-med-complex","status":"publish","type":"page","link":"https:\/\/pediatricbrainfoundation.org\/archive\/mediator-med-complex\/","title":{"rendered":"Mediator (MED) complex"},"content":{"rendered":"<div class=\"row-fluid\">\n<section class=\"span12\">\n<div class=\"back-link\"><a href=\"https:\/\/pediatricbrainfoundation.org\/archive\/educate\/glossary\/\">\u00ab Back to Glossary<\/a><\/div>\n<\/section><\/div>\n<div class=\"row-fluid\">\n<section class=\"content-top span12\">\n      <a id=\"main-content\"><\/a><\/p>\n<h1 class=\"page-header\">Mediator (MED) complex<\/h1>\n<\/section><\/div>\n<div class=\"row-fluid\">\n<section class=\"main-content span12\">\n<section id=\"block-system-main\" class=\"block-system block-page-content clearfix\">\n<div class=\"section-in\">\n<div class=\"section-inn\">\n<div class=\"section-innn\">\n<article id=\"node-5842\" class=\"node node-glossary-term clearfix\">\n  <!--\nTHIS FILE IS NOT USED AND IS HERE AS A STARTING POINT FOR CUSTOMIZATION ONLY.\nSee http:\/\/api.drupal.org\/api\/function\/theme_field\/7 for details.\nAfter copying this file to your theme's folder and customizing it, remove this\nHTML comment.\n--><\/p>\n<div id=\"body\" class=\"field field-name-body field-type-text-with-summary field-label-hidden prose\">\n<div class=\"field-items\">\n<div class=\"field-item even\">\n<p class=\"tkgyxz44ddvou8s4e\">\n<p class=\"tkgyxz44ddvou8s4e\">A mediator (MED) complex is a regulator of gene expression with a high degree of structural flexibility that regulates the ability for RNA polymerase II enzyme to express protein-coding genes. MED works with RNA polymerase II to read and transmit DNA information for cell division. These are targeted to control gene expression programs by responding to developmental or environmental cues.\u00a0<\/p>\n<p class=\"tkgyxz44ddvou8s4e\">Mediator is essential in converting biological inputs to physiological responses.\u00a0<\/p>\n<p class=\"tkgyxz44ddvou8s4e\">\n<\/div><\/div>\n<\/div>\n<p><!--\nTHIS FILE IS NOT USED AND IS HERE AS A STARTING POINT FOR CUSTOMIZATION ONLY.\nSee http:\/\/api.drupal.org\/api\/function\/theme_field\/7 for details.\nAfter copying this file to your theme's folder and customizing it, remove this\nHTML comment.\n--><\/p>\n<div id=\"field-term-source\" class=\"field field-name-field-term-source field-type-link-field field-label-hidden\">\n<div class=\"field-items\">\n<div class=\"field-item even\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20299225\" target=\"_blank\" rel=\"noopener\">NIH<\/a><\/div>\n<div class=\"field-item odd\"><a href=\"http:\/\/en.wikipedia.org\/wiki\/Mediator_(coactivator)\" target=\"_blank\" rel=\"noopener\">Wikipedia<\/a><\/div>\n<div class=\"field-item even\"><a href=\"http:\/\/informahealthcare.com\/doi\/full\/10.3109\/10409238.2013.840259\" target=\"_blank\" rel=\"noopener\">Informa Healthcare<\/a><\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n<p> <!-- \/.node -->\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<p> <!-- \/.block --><br \/>\n      <\/section>\n<\/p><\/div>\n","protected":false,"raw":""},"excerpt":{"rendered":"<p>\u00ab Back to Glossary Mediator (MED) complex A mediator [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template_2.php","meta":{"footnotes":""},"class_list":["post-452","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mediator (MED) complex | Pediatric Brain Foundation<\/title>\n<meta name=\"description\" content=\"A mediator (MED) complex is a regulator of gene expression with a high degree of structural flexibility that regulates the ability for RNA polymerase II enzyme to express protein-coding genes. MED works with RNA polymerase II to read and transmit DNA information for cell division. These are targeted to control gene expression programs by responding to developmental or\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pediatricbrainfoundation.org\/archive\/mediator-med-complex\/\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mediator (MED) complex | Pediatric Brain Foundation\" \/>\n<meta property=\"og:description\" content=\"A mediator (MED) complex is a regulator of gene expression with a high degree of structural flexibility that regulates the ability for RNA polymerase II enzyme to express protein-coding genes. MED works with RNA polymerase II to read and transmit DNA information for cell division. These are targeted to control gene expression programs by responding to developmental or\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pediatricbrainfoundation.org\/archive\/mediator-med-complex\/\" \/>\n<meta property=\"og:site_name\" content=\"Neurological Disorders\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Mediator (MED) complex | Pediatric Brain Foundation","description":"A mediator (MED) complex is a regulator of gene expression with a high degree of structural flexibility that regulates the ability for RNA polymerase II enzyme to express protein-coding genes. MED works with RNA polymerase II to read and transmit DNA information for cell division. These are targeted to control gene expression programs by responding to developmental or","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pediatricbrainfoundation.org\/archive\/mediator-med-complex\/","og_type":"article","og_title":"Mediator (MED) complex | Pediatric Brain Foundation","og_description":"A mediator (MED) complex is a regulator of gene expression with a high degree of structural flexibility that regulates the ability for RNA polymerase II enzyme to express protein-coding genes. MED works with RNA polymerase II to read and transmit DNA information for cell division. These are targeted to control gene expression programs by responding to developmental or","og_url":"https:\/\/pediatricbrainfoundation.org\/archive\/mediator-med-complex\/","og_site_name":"Neurological Disorders","twitter_card":"summary_large_image"},"_links":{"self":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/pages\/452","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/types\/page"}],"replies":[{"embeddable":true,"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/comments?post=452"}],"version-history":[{"count":0,"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/pages\/452\/revisions"}],"wp:attachment":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/media?parent=452"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}