{"id":426,"date":"2023-08-10T15:21:41","date_gmt":"2023-08-10T15:21:41","guid":{"rendered":"https:\/\/pediatricbrainfoundation.org\/archive\/germline-gene-therapy\/"},"modified":"2023-08-10T15:21:41","modified_gmt":"2023-08-10T15:21:41","slug":"germline-gene-therapy","status":"publish","type":"page","link":"https:\/\/pediatricbrainfoundation.org\/archive\/germline-gene-therapy\/","title":{"rendered":"Germline Gene Therapy"},"content":{"rendered":"
\n
\n
\u00ab Back to Glossary<\/a><\/div>\n<\/section><\/div>\n
\n
\n <\/a><\/p>\n

Germline Gene Therapy<\/h1>\n<\/section><\/div>\n
\n
\n
\n
\n
\n
\n
\n <\/p>\n
\n
\n
\n

\n

Germline gene therapy is a potential method of treatment for rare genetic disorders and other common diseases that delivers a specific gene to target cells that would change a person’s genomic structure. It has not been available outside of clinical trials.\u00a0<\/p>\n

Germline gene therapy modifies existing germ cells (sperm and egg) by introducing genes and integrating these genes into their genomes. This is envisioned to transfer inheritance to offspring, thereby changing those genes forever.<\/p>\n

Hurdles to germline gene therapy are influenced by how the gene is transferred to the cell, oftentimes through viruses which cause other responses.\u00a0<\/p>\n

\n<\/div><\/div>\n<\/div>\n

<\/p>\n

\n
\n
National Human Genome Research Institute<\/a><\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n


\n <\/section>\n<\/p><\/div>\n","protected":false,"raw":""},"excerpt":{"rendered":"

\u00ab Back to Glossary Germline Gene Therapy Germline gene […]<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template_2.php","meta":{"footnotes":""},"class_list":["post-426","page","type-page","status-publish","hentry"],"yoast_head":"\nGermline Gene Therapy | Pediatric Brain Foundation<\/title>\n<meta name=\"description\" content=\"Germline gene therapy is a potential method of treatment for rare genetic disorders and other common diseases that delivers a specific gene to target cells that would change a person's genomic structure. It has not been available outside of clinical trials. Germline gene therapy modifies existing germ cells (sperm and egg) by introducing genes and integrating these genes into\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pediatricbrainfoundation.org\/archive\/germline-gene-therapy\/\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Germline Gene Therapy | Pediatric Brain Foundation\" \/>\n<meta property=\"og:description\" content=\"Germline gene therapy is a potential method of treatment for rare genetic disorders and other common diseases that delivers a specific gene to target cells that would change a person's genomic structure. It has not been available outside of clinical trials. Germline gene therapy modifies existing germ cells (sperm and egg) by introducing genes and integrating these genes into\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pediatricbrainfoundation.org\/archive\/germline-gene-therapy\/\" \/>\n<meta property=\"og:site_name\" content=\"Neurological Disorders\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Germline Gene Therapy | Pediatric Brain Foundation","description":"Germline gene therapy is a potential method of treatment for rare genetic disorders and other common diseases that delivers a specific gene to target cells that would change a person's genomic structure. It has not been available outside of clinical trials. Germline gene therapy modifies existing germ cells (sperm and egg) by introducing genes and integrating these genes into","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pediatricbrainfoundation.org\/archive\/germline-gene-therapy\/","og_type":"article","og_title":"Germline Gene Therapy | Pediatric Brain Foundation","og_description":"Germline gene therapy is a potential method of treatment for rare genetic disorders and other common diseases that delivers a specific gene to target cells that would change a person's genomic structure. It has not been available outside of clinical trials. Germline gene therapy modifies existing germ cells (sperm and egg) by introducing genes and integrating these genes into","og_url":"https:\/\/pediatricbrainfoundation.org\/archive\/germline-gene-therapy\/","og_site_name":"Neurological Disorders","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"}},"_links":{"self":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/pages\/426","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/types\/page"}],"replies":[{"embeddable":true,"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/comments?post=426"}],"version-history":[{"count":0,"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/pages\/426\/revisions"}],"wp:attachment":[{"href":"https:\/\/pediatricbrainfoundation.org\/archive\/wp-json\/wp\/v2\/media?parent=426"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}