{"id":341,"date":"2023-08-10T15:21:29","date_gmt":"2023-08-10T15:21:29","guid":{"rendered":"https:\/\/pediatricbrainfoundation.org\/archive\/study-shows-autistic-brains-create-more-information-rest\/"},"modified":"2023-08-10T15:21:29","modified_gmt":"2023-08-10T15:21:29","slug":"study-shows-autistic-brains-create-more-information-rest","status":"publish","type":"page","link":"https:\/\/pediatricbrainfoundation.org\/archive\/study-shows-autistic-brains-create-more-information-rest\/","title":{"rendered":"Study Shows Autistic Brains Create More Information at Rest"},"content":{"rendered":"
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\u00ab Back to Scientific News<\/a><\/div>\n<\/section><\/div>\n
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Study Shows Autistic Brains Create More Information at Rest<\/h1>\n<\/section><\/div>\n
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\n Friday, January 31, 2014<\/span>  \u00b7  Posted by Case Western Reserve University <\/a> <\/div>\n

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Possible explanation for "withdrawal into self," a characteristic of the disorder<\/div>\n<\/p><\/div>\n<\/div>\n

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New research from Case Western Reserve University and University of Toronto neuroscientists finds that the brains of autistic children generate more information at rest \u2013 a 42% increase on average. The study offers a scientific explanation for the most typical characteristic of autism \u2013 withdrawal into one\u2019s own inner world. The excess production of information may explain a child\u2019s detachment from their environment.<\/p>\n

Published at the end of December in Frontiers in Neuroinformatics, this study is a follow-up to the authors\u2019 prior finding that brain connections are different in autistic children. This paper determined that the differences account for the increased complexity within their brains.<\/p>\n

\u201cOur results suggest that autistic children are not interested in social interactions because their brains generate more information at rest, which we interpret as more introspection in line with early descriptions of the disorder,\u201d said Roberto Fern\u00e1ndez Gal\u00e1n, PhD, senior author and associate professor of neurosciences at Case Western Reserve School of Medicine.<\/p>\n

The authors quantified information as engineers normally do but instead of applying it to signals in electronic devices, they applied it to brain activity recorded with magnetoencephalography (MEG). They showed that autistic children\u2019s brains at rest generate more information than non-autistic children. This may explain their lack of interest in external stimuli, including interactions with other people.<\/p>\n

The researchers also quantified interactions between brain regions, i.e., the brain’s functional connectivity, and determined the inputs to the brain in the resting state allowing them to interpret the children\u2019s introspection level.<\/p>\n

\u201cThis is a novel interpretation because it is a different attempt to understand the children\u2019s cognition by analyzing their brain activity,\u201d said Jos\u00e9 L. P\u00e9rez Vel\u00e1zquez, PhD, first author and professor of neuroscience at University of Toronto Institute of Medical Science and Department of Pediatrics, Brain and Behavior Center.<\/p>\n

\u201cMeasuring cognitive processes is not trivial; yet, our findings indicate that this can be done to some extent with well-established mathematical\u00a0tools from physics and engineering.\u201d<\/p>\n

This study provides quantitative support for the relatively new \u201cIntense World Theory\u201d of autism proposed by neuroscientists Henry and Kamila Markram of the Brain Mind Institute in Switzerland, which describes the disorder as the result of hyper-functioning neural circuitry, leading to a state of over-arousal. More generally, the work of Gal\u00e1n and P\u00e9rez Vel\u00e1zquez is an initial step in the investigation of how information generation in the brain relates to cognitive\/psychological traits and will begin to frame neurophysiological data into psychological aspects. The team now aims to apply a similar approach to patients with schizophrenia.<\/p>\n<\/div><\/div>\n<\/div>\n

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collaboration<\/a><\/div>\n
autism<\/a><\/div>\n
Autism Spectrum Disorders<\/a><\/div>\n
rest<\/a><\/div>\n
magnetoencephalography<\/a><\/div>\n
MEG<\/a><\/div>\n
external stimuli<\/a><\/div>\n
hyper-functioning neural circuitry<\/a><\/div>\n<\/p><\/div>\n<\/div>\n