{"id":1218,"date":"2023-08-10T15:23:41","date_gmt":"2023-08-10T15:23:41","guid":{"rendered":"https:\/\/pediatricbrainfoundation.org\/archive\/serotonin\/"},"modified":"2023-08-10T15:23:41","modified_gmt":"2023-08-10T15:23:41","slug":"serotonin","status":"publish","type":"page","link":"https:\/\/pediatricbrainfoundation.org\/archive\/serotonin\/","title":{"rendered":"Serotonin"},"content":{"rendered":"
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Molecular time signaling controls stem cells during brain development<\/a><\/h2>\n
\n Thursday, November 13, 2014<\/span>  \u00b7  Posted by Karolinska Institute<\/a> <\/div>\n

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In a study being published in the journal Neuron, researchers show that the signal molecule TGF-beta acts as a time signal that regulates the nerve stem cells’ potential at different stages of the brain’s development \u2013 knowledge that may be significant for future pharmaceutical development.<\/p>\n<\/div><\/div>\n<\/div>\n<\/article>\n

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Johns Hopkins Bloomberg School of Public Health Researchers Find Association Between SSRI Use During Pregnancy and Autism and Developmental Delays in Boys<\/a><\/h2>\n
\n Tuesday, April 15, 2014<\/span>  \u00b7  Posted by Johns Hopkins University <\/a> <\/div>\n

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In a study of nearly 1,000 mother-child pairs, researchers from the Bloomberg School of Public health found that prenatal exposure to selective serotonin reuptake inhibitors (SSRIs), a frequently prescribed treatment for depression, anxiety and other disorders, was associated with autism spectrum disorder (ASD) and developmental delays (DD) in boys. <\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Brainstem abnormalities found in ‘SIDS’ infants, in both safe and unsafe sleep environments<\/a><\/h2>\n
\n Monday, November 11, 2013<\/span>  \u00b7  Posted by Boston Children’s Hospital<\/a> <\/div>\n

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The investigators, led by Hannah Kinney, MD, a neuropathologist at Boston Children’s, have shown over the past two decades that infants who die suddenly, unexpectedly and without explanation\u2014whose deaths are generally attributed to sudden infant death syndrome (SIDS)\u2014have differences in brainstem chemistry that set them apart from infants dying of other causes.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Birth gets the brain ready to sense the world<\/a><\/h2>\n
\n Monday, October 14, 2013<\/span>  \u00b7  Posted by Cell Press<\/a> <\/div>\n

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“Our results clearly demonstrate that birth has active roles in brain formation and maturation,” says senior study author Hiroshi Kawasaki of Kanazawa University in Japan. “We found that birth regulates neuronal circuit formation not only in the somatosensory system but also in the visual system. Therefore, it seems reasonable to speculate that birth actually plays a wider role in various brain regions.”<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Some autism behaviors linked to altered gene<\/a><\/h2>\n
\n Tuesday, February 12, 2013<\/span>  \u00b7  Posted by Washington University School of Medicine<\/a> <\/div>\n

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“Our results suggest that we have found a mechanism by which a genetic mutation can disrupt serotonin signaling and lead to behavior that is characteristic of autism,” Dougherty says. “Serotonin signaling is just one biological pathway that can be interrupted in patients with autism. We think similar investigations can find other pathways that may be important in this disease.”<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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