{"id":1215,"date":"2023-08-10T15:23:41","date_gmt":"2023-08-10T15:23:41","guid":{"rendered":"https:\/\/pediatricbrainfoundation.org\/archive\/seizures\/"},"modified":"2023-08-10T15:23:41","modified_gmt":"2023-08-10T15:23:41","slug":"seizures","status":"publish","type":"page","link":"https:\/\/pediatricbrainfoundation.org\/archive\/seizures\/","title":{"rendered":"Seizures"},"content":{"rendered":"
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UC Davis investigational medication used to resolve life-threatening seizures in children<\/a><\/h2>\n
\n Wednesday, November 12, 2014<\/span>  \u00b7  Posted by University of California, Davis<\/a> <\/div>\n

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The investigational formulation of\u00a0allopregnanolone was manufactured by UC Davis Health System’s Good Manufacturing Practice Laboratory. Two children were treated with the allopregnanolone formulation, one at UC Davis Children\u2019s Hospital, the other at the Ann & Robert Lurie Children\u2019s Hospital in Chicago. Both children were weaned from general anesthetics and other seizure treatments and their seizures resolved. In both instances the children are recovering.<\/p>\n<\/div><\/div>\n<\/div>\n<\/article>\n

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You Don’t Walk Alone<\/a><\/h2>\n
\n Saturday, September 13, 2014<\/span>  \u00b7  Posted by World Scientific<\/a> <\/div>\n

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65 MILLION people around the world today suffer from epilepsy, a condition of the brain that may trigger an uncontrollable seizure at any time, often for no known reason. A seizure is a disruption of the electrical communication between neurons, and someone is said to have epilepsy if they experience two or more unprovoked seizures separated by at least 24 hours.<\/p>\n<\/div><\/div>\n<\/div>\n<\/article>\n

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Probing Brain\u2019s Depth, Trying to Aid Memory <\/a><\/h2>\n
\n Wednesday, July 9, 2014<\/span>  \u00b7  Posted by New York Times <\/a> <\/div>\n

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The Department of Defense on Tuesday announced a $40 million investment in what has become the fastest-moving branch of neuroscience: direct brain recording. Two centers, one at the University of Pennsylvania and the other at the University of California, Los Angeles, won contracts to develop brain implants for memory deficits.
\nTheir aim is to develop new treatments for traumatic brain injury, the signature wound of the wars in Iraq and in Afghanistan. Its most devastating symptom is the blunting of memory and reasoning. Scientists have found in preliminary studies that they can sharpen some kinds of memory by directly recording, and stimulating, circuits deep in the brain.
\nUnlike brain imaging, direct brain recording allows scientists to conduct experiments while listening to the brain\u2019s internal dialogue in real time, using epilepsy patients like Ralph or people with Parkinson\u2019s disease as active collaborators.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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University of Toronto biologists pave the way for improved epilepsy treatments<\/a><\/h2>\n
\n Thursday, June 5, 2014<\/span>  \u00b7  Posted by University of Toronto<\/a> <\/div>\n

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Three key proteins \u2013 KCC2, Neto2 and GluK2 \u2013 required for inhibitory and excitatory synaptic communication. KCC2 is required for inhibitory impulses, GluK2 is a receptor for the main excitatory transmitter glutamate, and Neto2 is an auxiliary protein that interacts with both KCC2 and GluK2. The discovery of the complex of three proteins is pathbreaking as it was previously believed that KCC2 and GluK2 were in separate compartments of the cell and acted independently of each other.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Neuroscience\u2019s grand question <\/a><\/h2>\n
\n Wednesday, May 21, 2014<\/span>  \u00b7  Posted by Brandeis University <\/a> <\/div>\n

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Neurons live for many years but their components, the proteins and molecules that make up the cell are continually being replaced. How this continuous rebuilding takes place without affecting our ability to think, remember, learn or otherwise experience the world is one of neuroscience\u2019s biggest questions.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Genetic legacy from the Ottoman Empire: Single mutation causes rare brain disorder <\/a><\/h2>\n
\n Thursday, April 24, 2014<\/span>  \u00b7  Posted by Yale University <\/a> <\/div>\n

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An international team of researchers have identified a previously unknown neurodegenerative disorder and discovered it is caused by a single mutation in one individual born during the height of the Ottoman Empire in Turkey about 16 generations ago.The genetic cause of the rare disorder was discovered during a massive analysis of the individual genomes of thousands of Turkish children suffering from neurological disorders.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Researchers Discover New Genetic Brain Disorder in Humans <\/a><\/h2>\n
\n Thursday, April 24, 2014<\/span>  \u00b7  Posted by University of California, San Diego <\/a> <\/div>\n

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By performing DNA sequencing of more than 4,000 families affected by neurological problems, the two research teams independently discovered that a disease marked by reduced brain size and sensory and motor defects is caused by a mutation in a gene called CLP1, which is known to regulate tRNA metabolism in cells. Insights into this rare disorder, the researchers said, may have important implications for the future treatment of more common neurological conditions.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Newly-Approved Brain Stimulator Offers Hope for Individuals With Uncontrolled Epilepsy <\/a><\/h2>\n
\n Monday, April 21, 2014<\/span>  \u00b7  Posted by Rush University Medical Center <\/a> <\/div>\n

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A recently FDA-approved device has been shown to reduce seizures in patients with medication-resistant epilepsy by as much as 50 percent. When coupled with an innovative electrode placement planning system developed by physicians at Rush, the device facilitated the complete elimination of seizures in nearly half of the implanted Rush patients enrolled in the decade-long clinical trials.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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2014 March of Dimes Prize in Developmental Biology<\/a><\/h2>\n
\n Tuesday, April 15, 2014<\/span>  \u00b7  Posted by Lindsey Wiltse, Communications and Program Coordinator <\/div>\n

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The 2014 March of Dimes Prize in Developmental Biology will be awarded May 5, 2014 to Dr. Huda Zoghbi, a pioneer in the recognition and development of treatment for Rett Syndrome. <\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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Young people with epilepsy significantly more at risk of injury <\/a><\/h2>\n
\n Monday, April 14, 2014<\/span>  \u00b7  Posted by The University of Nottingham <\/a> <\/div>\n

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The authors say that doctors and other healthcare professionals can use the findings of the research to make children and young adults diagnosed with epilepsy, and their parents, more aware of the risk of injury and to inform existing guidelines on treatment. In particular, they cite the need for more information relating to the safe storage of medicines and the supervision of children while taking their medication to be given by doctors at the time of prescribing and by pharmacists when dispensing prescriptions.<\/div>\n<\/p><\/div>\n<\/div>\n<\/article>\n

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