{"id":1100,"date":"2023-08-10T15:23:32","date_gmt":"2023-08-10T15:23:32","guid":{"rendered":"https:\/\/pediatricbrainfoundation.org\/archive\/mouse-model\/"},"modified":"2023-08-10T15:23:32","modified_gmt":"2023-08-10T15:23:32","slug":"mouse-model","status":"publish","type":"page","link":"https:\/\/pediatricbrainfoundation.org\/archive\/mouse-model\/","title":{"rendered":"Mouse model"},"content":{"rendered":"
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How does the brain develop in individuals with autism?<\/a><\/h2>\n
\n Wednesday, November 12, 2014<\/span>  \u00b7  Posted by Heidelberg University<\/a> <\/div>\n

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Geneticists at Heidelberg University Hospital\u2019s Department of Molecular Human Genetics have used a new mouse model to demonstrate the way a certain genetic mutation is linked to a type of autism in humans and affects brain development and behavior. In the brain of genetically altered mice, the protein FOXP1 is not synthesized, which is also the case for individuals with a certain form of autism. Consequently, after birth the brain structures degenerate that play a key role in perception. The mice also exhibited abnormal behavior that is typical of autism.<\/p>\n<\/div><\/div>\n<\/div>\n<\/article>\n

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