Findings can help in patient treatment and in development of injury-prevention programs
This week’s issue of the New England Journal of Medicine features an article that highlights an unprecedented analysis of the nation’s childhood head injuries. The study, authored by physicians at UC Davis School of Medicine and Washington University School of Medicine, analyzed more than 43,000 children who were evaluated for head trauma at 25 emergency departments around the United States.
The only drug currently approved for treatment of stroke’s crippling effects shows promise, when administered as a nasal spray, to help heal similar damage in less severe forms of traumatic brain injury.
In the first examination of its kind, researchers Ye Xiong, Ph.D, Zhongwu Liu, Ph.D., and Michael Chopp, Ph.D., Scientific Director of the Henry Ford Neuroscience Institute, found in animal studies that the brain’s limited ability to repair itself after trauma can be enhanced when treated with the drug tPA, or tissue plasminogen activator.
The potential for doctors to measure damaging "brain tsunamis” in injured patients without opening the skull has moved a step closer to reality, thanks to pioneering research at the University of Cincinnati (UC) Neuroscience Institute.